Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274358 | 1.00 | ESR1 (0.48) | ESR1ESR2KCNA5EDNRALTA4H | |
| SCHEMBL25986540 | 0.88 | ESR1 (0.60) | ESR1ESR2LTA4HALDH1A1GAA | |
| SCHEMBL25919777 | 0.88 | ESR1 (0.60) | ESR1ESR2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12267815 | 0.84 | ESR1 (0.46) | ESR1ESR2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10093721 | 0.84 | ESR1 (0.46) | ESR1ESR2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10000525 | 0.83 | ESR1 (0.66) | ESR1ESR2ALDH1A1GAACYP19A1 | |
| SCHEMBL14592267 | 0.83 | KCNA5 (0.40) | KCNA5EDNRALTA4HLMNASMN1; SMN2 | |
| SCHEMBL10175309 | 0.83 | ESR1 (0.55) | ESR1ESR2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14518073 | 0.82 | ESR1 (0.46) | ESR1ESR2LTA4HALDH1A1GAA | |
| SCHEMBL19200619 | 0.79 | ESR1 (0.72) | ESR1ESR2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036041-A1 | MOLDING MATERIALS COMPRISING HIGHLY CROSSLINKED ORGANIC NANOPARTICLES | BASF SE (DE) | 2010-02-11 | — | — | US | disclosed |