SCHEMBL25986540

SCHEMBL25986540

COc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(OC)cc5)cc4)CC(C)CC(C)(C)C3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
LTA4H P09960 2/20 0.38
CHRNA1 P02708 1/20 0.37
CHRNG P07510 1/20 0.37
CHRNB1 P11230 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
CHRND Q07001 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HTT P42858 1/20 0.36
BACE1 P56817 1/20 0.35
TSHR P16473 1/20 0.34
GAA P10253 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000525 0.95 ESR1 (0.66) ESR1ESR2MAOBMAOACHRNA1
SCHEMBL17081749 0.90 ESR1 (0.50) ESR1ESR2MAOBMAOALTA4H
SCHEMBL12177591 0.88 ESR2 (0.80) ESR1ESR2MAOBMAOALTA4H
SCHEMBL25919777 0.88 ESR1 (0.60) ESR1ESR2MAOBMAOACHRNA1
SCHEMBL14274358 0.88 ESR1 (0.48) ESR1ESR2MAOBMAOALTA4H
SCHEMBL13508245 0.88 ESR1 (0.48) ESR1ESR2MAOBMAOALTA4H
SCHEMBL13382522 0.86 ESR1 (0.55) ESR1ESR2MAOBMAOAKMT2A
SCHEMBL10175309 0.86 ESR1 (0.55) ESR1ESR2MAOBMAOACHRNA1
SCHEMBL14064751 0.86 ESR1 (0.49) ESR1ESR2CHRNA1CHRNGCHRNB1
SCHEMBL20169141 0.86 ESR1 (0.46) ESR1ESR2LTA4HHTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed