SCHEMBL1350834

SCHEMBL1350834

CCC(C)C(=O)OC1CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
CYP19A1 P11511 1/20 0.41
NAAA Q02083 2/20 0.41
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
ADRA1A P35348 1/20 0.36
CHRNA4 P43681 1/20 0.36
HTR3A P46098 1/20 0.36
KCNH2 Q12809 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
EPHX2 P34913 2/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
TPSAB1 Q15661 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2681050 0.96 EPHX1 (0.47) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL786258 0.94 EPHX1 (0.50) EPHX1CYP19A1NAAAL3MBTL1HTT
SCHEMBL10900145 0.92 CHRM2 (0.38) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL18253326 0.87 EPHX1 (0.35) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL27803283 0.86 SMN1; SMN2 (0.34) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL18253439 0.85 CYP2C19 (0.37) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL2754975 0.85 SHBG (0.39) EPHX1CYP19A1CHRM2CHRM1CHRM3
SCHEMBL18119958 0.85 CHRM2 (0.34) EPHX1CYP19A1NAAACHRM2CHRM1
SCHEMBL6721426 0.85 CYP19A1 (0.40) EPHX1CYP19A1CHRM2CHRM1CHRM3
SCHEMBL13073273 0.85 CYP19A1 (0.40) EPHX1CYP19A1CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103796989-B Branched 3-phenylpropionic acid derivatives and uses thereof 拜耳知识产权有限责任公司 2017-03-01 CN disclosed
EP-2143711-B1 Actinic ray-sensitive or radiation-sensitive resin composition and pattern forming method using same FUJIFILM CORP (JP) 2016-12-21 EP disclosed
CN-103796989-A Branched 3-phenylpropionic acid derivatives and uses thereof BAYER IP GMBH 2014-05-14 CN disclosed
US-8062651-B1 Attractant pheromone for the male pink hibiscus mealybug, Maconellicoccus hirsutus (Green) (Homoptera: Pseudococcidae) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2011-11-22 US disclosed