Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685186 | 1.00 | ESR1 (0.47) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3696699 | 0.88 | ESR1 (0.46) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL14527871 | 0.82 | ESR1 (0.53) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL5974797 | 0.82 | ESR1 (0.55) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL12059023 | 0.80 | ESR1 (0.54) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3696702 | 0.80 | ESR1 (0.46) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL13508358 | 0.80 | ESR1 (0.43) | ESR1ALDH1A1PPARDMAPK1 | |
| SCHEMBL3686106 | 0.80 | ESR1 (0.43) | ESR1ALDH1A1PPARDMAPK1 | |
| SCHEMBL6129079 | 0.78 | ESR1 (0.52) | ESR1ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL13508360 | 0.78 | LMNA (0.50) | ESR1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |