SCHEMBL13508364

SCHEMBL13508364

Cc1cc(S[C@H](C)CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.56
PPARA Q07869 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685122 1.00 PPARD (0.56) PPARDPPARA
SCHEMBL13509516 0.85 PPARD (0.60) PPARDPPARA
SCHEMBL3691720 0.80 PPARD (0.53) PPARDPPARA
SCHEMBL13508254 0.80 PPARD (0.53) PPARDPPARA
SCHEMBL3690248 0.79 PPARD (0.54) PPARDPPARA
SCHEMBL13508349 0.79 PPARD (0.54) PPARDPPARA
SCHEMBL13508360 0.79 LMNA (0.50) PPARD
SCHEMBL4839977 0.77 PPARD (0.73) PPARDPPARA
SCHEMBL13509393 0.75 PPARD (0.55) PPARDPPARA
SCHEMBL3866654 0.74 PPARD (0.68) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7655641-B2 Sulfonamide derivatives as PPAR modulators ELI LILLY AND COMPANY (US) 2010-02-02 US disclosed