Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 10/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 10/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508503 | 0.85 | PFKFB3 (0.41) | PFKFB3GABRA1MMP8MMP3PPARG | |
| SCHEMBL13508450 | 0.84 | PPARG (0.42) | PFKFB3GABRA1MMP8MMP3PPARG | |
| SCHEMBL13508487 | 0.84 | PPARG (0.42) | PFKFB3PPARGPPARAPPARD | |
| SCHEMBL13508496 | 0.71 | CYP1A2 (0.48) | MMP8MMP3PPARGPPARAPPARD | |
| SCHEMBL2197561 | 0.69 | GABRA1 (0.59) | PFKFB3GABRA1MMP8MMP3CCKBR | |
| SCHEMBL13508500 | 0.68 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL13508430 | 0.68 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL13508556 | 0.67 | PTPN7 (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3683822 | 0.67 | PFKFB3 (0.41) | PFKFB3GABRA1MMP8MMP3PPARG | |
| SCHEMBL13508433 | 0.67 | PPARA (0.43) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |