Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 5/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756003 | 0.83 | PPARA (0.41) | CMA1PPARAPPARDPPARGMEN1 | |
| SCHEMBL3691319 | 0.82 | PPARA (0.42) | CMA1PPARAPPARDPPARGMEN1 | |
| SCHEMBL3687645 | 0.82 | PPARD (0.41) | PPARAPPARDPPARGPFKFB3PFKFB4 | |
| SCHEMBL13508526 | 0.81 | PPARA (0.40) | CMA1PPARAPPARDPPARGMEN1 | |
| SCHEMBL3683343 | 0.80 | PPARA (0.41) | CMA1PPARAPPARDPPARGMEN1 | |
| SCHEMBL13508556 | 0.79 | PTPN7 (0.44) | PPARAPPARDPPARGPTPN7DUSP3 | |
| SCHEMBL3683718 | 0.77 | PPARD (0.51) | PPARDPPARGPFKFB3PFKFB4 | |
| SCHEMBL3695390 | 0.77 | PPARD (0.43) | CMA1PPARDPPARGPFKFB3PFKFB4 | |
| SCHEMBL3685095 | 0.77 | PPARA (0.49) | CMA1PPARAPPARDPPARGPFKFB3 | |
| SCHEMBL3689854 | 0.76 | HTR6 (0.40) | CMA1PFKFB3PFKFB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |