Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 11/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 7/20 | 1.00 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.86 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.73 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylbutyrylhydroxamic Acid SCHEMBL27961036 | 0.98 | HDAC1 (0.96) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5020669 | 0.96 | HDAC1 (0.93) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5020670 | 0.96 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5020559 | 0.94 | HDAC1 (0.96) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL3844327 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5807174 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL22190384 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL8610138 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL7043051 | 0.89 | HDAC2 (0.90) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL1980549 | 0.89 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554069-A | Preparation method and preparation equipment of formate compound | 绍兴贝斯美化工股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-110015974-A | A kind of preparation method of cyclododecanone oxime | 万华化学集团股份有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-107488090-A | A kind of efficient catalytic asymmetry preparation method of N cyclopropyl nitrone compound | 东北师范大学 | 2017-12-19 | — | — | CN | claimed |
| CN-106146350-B | A kind of new method of synthesizing amino formic acid oxime ester derivative | 华南理工大学 | 2017-10-20 | — | — | CN | claimed |
| CN-107011201-A | Preparation method of amide | 南京工业大学 | 2017-08-04 | — | — | CN | claimed |
| CN-106146350-A | A kind of new method of synthesizing amino methylcarbamoyl oximino ester derivant | 华南理工大学 | 2016-11-23 | — | — | CN | claimed |
| CN-116554069-A | Preparation method and preparation equipment of formate compound | 绍兴贝斯美化工股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| US-20220048988-A1 | CELLS EXPRESSING ANTIBODIES TARGETING HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USING THE SAME | CHILDREN'S NATIONAL MEDICAL CENTER | 2022-02-17 | — | — | US | disclosed |
| EP-3849607-A1 | CELLS COMPRISING ANTIBODIES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF PREPARING AND USING THE SAME | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20210040184-A1 | ANTI-HIV ANTIBODIES | ATRECA INC (US) | 2021-02-11 | — | — | US | disclosed |
| US-20210040185-A1 | ANTI-HIV ANTIBODIES | ATRECA INC (US) | 2021-02-11 | — | — | US | disclosed |
| EP-1107953-A1 | HYDROXAMIC ACID DERIVATIVES AS PROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012477-A1 | HYDROXAMIC ACID DERIVATIVES AS PROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| CN-1029613-C | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflamatory agents | AMERICAN HOME PROD (US) | 1995-08-30 | — | — | CN | disclosed |
| CN-1058771-A | Method for making of oxime carbamate and oxime carbonate ester and uses thereof | AMERICAN HOME PROD (US) | 1992-02-19 | — | — | CN | disclosed |
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | HDAC1 1597/4885HDAC2 2165/4885HDAC8 2653/4885 |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | HDAC1 1465/4885HDAC2 1983/4885HDAC8 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.