Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 9/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 1/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.86 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.86 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.86 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.76 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807174 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL3844327 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL22190384 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020559 | 0.98 | HDAC1 (0.96) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020670 | 0.93 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Phenylbutyrylhydroxamic Acid SCHEMBL1350853 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Phenylbutyrylhydroxamic Acid SCHEMBL27961036 | 0.91 | HDAC1 (0.96) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL1232766 | 0.91 | HDAC1 (0.83) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL12889789 | 0.90 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020668 | 0.89 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845734-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | King Faisal University (SA) | 2023-12-19 | — | — | US | disclosed |
| US-11773111-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | King Faisal University (SA) | 2023-10-03 | — | — | US | disclosed |
| US-11724991-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | King Faisal University (SA) | 2023-08-15 | — | — | US | disclosed |
| EP-0831796-A1 | METHOD FOR REDUCING OR PREVENTING POST-SURGICAL ADHESION FORMATION USING 5-LIPOXYGENASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040090-A1 | METHOD FOR REDUCING OR PREVENTING POST-SURGICAL ADHESION FORMATION USING 5-LIPOXYGENASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0273451-B1 | LIPOXYGENASE INHIBITORY COMPOUNDS | Bristol-Myers Squibb Company (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4861798-A | Lipoxygenase inhibitory compounds | BRISTOL-MYERS COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0273451-A2 | Lipoxygenase inhibitory compounds | Bristol-Myers Squibb Company (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4731382-A | Lipoxygenase inhibitory phenylalkanohydroxamic acids | BRISTOL-MYERS COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773111-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | ALOX5, LTC4S, NOX5 | HDAC1 1167/4885HDAC2 887/4885ALOX5 1/4885 |
| US-11724991-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | ALOX5, LTC4S, NOX5 | HDAC1 906/4885HDAC2 897/4885ALOX5 1/4885 |
| US-11845734-B1 | Selective 5-LO inhibitors for the treatment of bronchial asthma | ALOX5, LTC4S, NOX5 | HDAC1 906/4885HDAC2 897/4885ALOX5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.