Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 9/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 1/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.86 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.86 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.86 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.76 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807174 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL8610138 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL3844327 | 1.00 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020559 | 0.98 | HDAC1 (0.96) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020670 | 0.93 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Phenylbutyrylhydroxamic Acid SCHEMBL1350853 | 0.92 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Phenylbutyrylhydroxamic Acid SCHEMBL27961036 | 0.91 | HDAC1 (0.96) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL1232766 | 0.91 | HDAC1 (0.83) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL12889789 | 0.90 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL5020668 | 0.89 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |