Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688162 | 0.79 | ALDH1A1 (0.45) | ALDH1A1PLA2G1BATG4BGAAKDM4E | |
| SCHEMBL13508417 | 0.79 | POLB (0.48) | ALDH1A1GAAKDM4EMAPTNPSR1 | |
| SCHEMBL13508419 | 0.78 | POLB (0.47) | ALDH1A1PLA2G1BATG4BGAAKDM4E | |
| SCHEMBL13508422 | 0.75 | PPARG (0.47) | ALDH1A1GAAKDM4EMAPTNPSR1 | |
| SCHEMBL3680899 | 0.73 | PPARD (0.53) | ALDH1A1GAAKDM4EMAPTNPSR1 | |
| SCHEMBL13508421 | 0.72 | PPARG (0.51) | GAAMAPTNPSR1POLB | |
| SCHEMBL13509569 | 0.71 | LMNA (0.45) | ALDH1A1PLA2G1BATG4BLMNATSHR | |
| SCHEMBL13508491 | 0.70 | PPARG (0.49) | GAAMAPTNPSR1POLB | |
| SCHEMBL13508418 | 0.69 | PPARG (0.51) | GAAMAPTNPSR1POLBBCHE | |
| SCHEMBL20021985 | 0.67 | SLC6A2 (0.60) | ALDH1A1PLA2G1BATG4BL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |