Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 19/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 14/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.55 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.55 |
| ▸ | RPS27 | P42677 | 5/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514107 | 0.86 | MAPK8 (0.52) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL13514177 | 0.83 | MAPK8 (0.59) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL1145009 | 0.81 | MAPK8 (0.60) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL20606873 | 0.80 | MAPK8 (0.59) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL1145693 | 0.79 | MAPK8 (0.61) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL13514109 | 0.75 | RPS27 (0.67) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL13514544 | 0.75 | MAPK8 (0.75) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL1146017 | 0.74 | MAPK8 (0.74) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL1145329 | 0.74 | MAPK8 (0.74) | MAPK8MAPK9MAPK10PRKD3PRKD2 | |
| SCHEMBL31060560 | 0.73 | MAPK8 (0.52) | MAPK8MAPK9MAPK10PRKD3PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007756-A1 | PYRIDINE DERIVATIVE HAVING TTK INHIBITION ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-01-21 | — | — | WO | disclosed |