Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13515153 | 0.97 | KMT2A (0.46) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL1719912 | 0.93 | GAA (0.49) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL14650157 | 0.87 | ALDH1A1 (0.45) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL6314895 | 0.86 | KMT2A (0.49) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL13515150 | 0.80 | KMT2A (0.44) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL8539138 | 0.80 | KMT2A (0.44) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL5730753 | 0.79 | KMT2A (0.43) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL2926559 | 0.79 | KMT2A (0.43) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL3283828 | 0.76 | CASP3 (0.41) | KMT2AHSD17B10GAAMAPTNPC1 | |
| SCHEMBL13515136 | 0.76 | HTT (0.42) | KMT2AHSD17B10GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461341-B1 | PROCESS FOR PREPARING A HETEROAROMATIC COMPOUND SUBSTITUTED WITH ONE OR MORE ETHER GROUPS | AGFA GEVAERT (BE) | 2010-01-27 | — | — | EP | disclosed |