Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25083059 | 0.85 | MAP2K1 (0.49) | MAP2K1KDM4EALOX15HTTTDP1 | |
| SCHEMBL30390278 | 0.85 | MAP2K1 (0.49) | MAP2K1KDM4EALOX15HTTTDP1 | |
| SCHEMBL27402379 | 0.84 | MAP2K1 (0.48) | MAP2K1KDM4EALOX15HTTTDP1 | |
| SCHEMBL2936605 | 0.79 | NQO2 (0.48) | KDM4EALOX15HTTNQO2ABL1 | |
| SCHEMBL13515356 | 0.78 | KDM4E (0.47) | MAP2K1KDM4EALOX15HTTNQO2 | |
| SCHEMBL16915063 | 0.77 | KDM4E (0.55) | MAP2K1KDM4EALOX15HTTTDP1 | |
| SCHEMBL4076248 | 0.74 | ALOX15 (0.46) | MAP2K1KDM4EALOX15HTTNR4A2 | |
| SCHEMBL13515345 | 0.73 | ALOX15 (0.58) | MAP2K1KDM4EALOX15HTTABL1 | |
| SCHEMBL4077038 | 0.73 | HTT (0.45) | MAP2K1KDM4EALOX15HTTNR4A2 | |
| SCHEMBL25082893 | 0.73 | NQO2 (0.42) | KDM4ENR4A2NQO2ABL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580785-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-11-12 | — | — | US | disclosed |
| EP-1919903-B1 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | MAP2K1 4342/4885KDM4E 3002/4885ALOX15 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.