Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529033 | 0.95 | L3MBTL1 (0.46) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 | |
| SCHEMBL16387906 | 0.86 | HRH3 (0.41) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 | |
| SCHEMBL29750851 | 0.85 | HRH3 (0.36) | L3MBTL3L3MBTL1CYP2D6CYP2C19HRH3 | |
| SCHEMBL1813299 | 0.85 | — | — | |
| SCHEMBL26117153 | 0.85 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 | |
| SCHEMBL26112589 | 0.85 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 | |
| Methane SCHEMBL15974763 | 0.82 | — | — | |
| SCHEMBL20756261 | 0.82 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 | |
| SCHEMBL827994 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL31467080 | 0.82 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1CYP2D6CYP2C19MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |