Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745049 | 0.85 | GLA (0.50) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL2949425 | 0.83 | GLA (0.53) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL24911981 | 0.80 | GLA (0.46) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7027263 | 0.79 | GLA (0.67) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL3973280 | 0.79 | GLA (0.67) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL6536452 | 0.79 | GLA (0.67) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL1069692 | 0.79 | — | — | |
| Isobutanol SCHEMBL9242794 | 0.79 | GLA (0.52) | GLACYP1A2SMN1; SMN2MAPK1APEX1 | |
| Propane SCHEMBL1995071 | 0.78 | GLA (0.59) | GLACYP1A2SMN1; SMN2MAPK1LMNA | |
| Ammonia Solution, Strong SCHEMBL9352555 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |