Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665212 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13665211 | 0.87 | SORT1 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13665241 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13665204 | 0.84 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13515796 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL2945692 | 0.84 | SMN1; SMN2 (0.74) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL2947441 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13665243 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL2953893 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL13665215 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489078-B1 | BENZOFURAN DERIVATIVE | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-01-06 | — | — | EP | disclosed |