Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903153 | 0.81 | KMT2A (0.61) | KMT2AMEN1ACHEALDH1A1POLB | |
| SCHEMBL3821816 | 0.79 | KMT2A (0.68) | KMT2AMEN1ALDH1A1POLBMAOB | |
| SCHEMBL7564693 | 0.74 | LCK (0.47) | KMT2AMEN1ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL28636011 | 0.73 | KMT2A (0.58) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28920273 | 0.71 | MEN1 (0.66) | KMT2AMEN1BCHEACHEALDH1A1 | |
| SCHEMBL9903546 | 0.71 | PTGDR2 (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15776394 | 0.71 | KMT2A (0.59) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3739838 | 0.70 | KIF11 (0.49) | KMT2AMEN1MAOB | |
| SCHEMBL28632725 | 0.70 | MEN1 (0.53) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14783795 | 0.69 | MEN1 (0.61) | KMT2AMEN1ACHEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023847-B2 | Azaheterocyclic compounds | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | PCNA, MCL1, MYC | KMT2A 793/4885MEN1 1021/4885BCHE 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.