SCHEMBL1351968

SCHEMBL1351968

Nc1ccc(Cc2ccc(N)cc2[N+](=O)[O-])c([N+](=O)[O-])c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
TDP1 Q9NUW8 4/20 0.62
CYP3A4 P08684 2/20 0.62
ALOX15 P16050 2/20 0.62
TSHR P16473 4/20 0.58
MAPK1 P28482 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
RECQL P46063 1/20 0.58
HSD17B10 Q99714 1/20 0.58
SNCA P37840 2/20 0.50
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
POLB P06746 2/20 0.42
CYP1A2 P05177 1/20 0.42
MCL1 Q07820 1/20 0.42
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
PDE7A Q13946 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389163 1.00 ALDH1A1 (0.62) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL38658431 0.90 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL18399383 0.90 TSHR (0.57) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL30932716 0.89 ALDH1A1 (0.55) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL867821 0.89 ALDH1A1 (0.55) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL358991 0.86 ALDH1A1 (0.61) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL7218334 0.86 ALDH1A1 (0.60) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL3721040 0.85 ALDH1A1 (0.58) ALDH1A1TDP1CYP3A4ALOX15TSHR
SCHEMBL8744287 0.85 ALOX15 (0.59) ALDH1A1TDP1CYP3A4ALOX15TSHR
Hydrochloric Acid SCHEMBL28234289 0.85 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4942093-A COMPOSITES, THERMOSETTING RESINS, A BISMALEIMIDE COMPOUND AND AN ISOCYANATE TERMINATED RUBBER BONDED TO A POLYURETHANES, TIR ES BRIDGESTONE/FIRESTONE, INC. (US) 1990-07-17 US claimed
EP-0358084-A2 An adhesive system for bonding uncured rubber to cured polyurethane BRIDGESTONE/FIRESTONE, INC. (US) 1990-03-14 EP claimed
EP-3760674-B1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN IND LTD (JP) 2024-12-18 EP disclosed
EP-3822315-B1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN IND LTD (JP) 2024-09-11 EP disclosed
US-11999842-B2 Thermoplastic resin composition comprising a fluororesin and a crosslinked fluoroelastomer and method for producing the same DAIKIN INDUSTRIES, LTD. (JP) 2024-06-04 US disclosed
US-11787927-B2 Thermoplastic resin composition and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-10-17 US disclosed
US-20210301118-A1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-09-30 US disclosed
EP-3822315-A1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-05-19 EP disclosed
US-20210040302-A1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING DAIKIN INDUSTRIES, LTD. (JP) 2021-02-11 US disclosed
EP-3760674-A1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-01-06 EP disclosed
US-20170107328-A1 POLYMERS FROM STABILIZED IMINES INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-20 US disclosed
US-5108460-A Having at least one polyoxyalkylene substituents, useful with fibers like polyamides cotton, wool, silk and nylon MILLIKEN RESEARCH CORPORATION (US) 1992-04-28 US disclosed
EP-0137489-B1 POLYISOCYANURATE FOAM PREPARED FROM AN ALKOXYLATED AROMATIC AMINE-AROMATIC POLYESTER POLYOL BLEND THE CELOTEX CORPORATION (US) 1991-06-19 EP disclosed
US-4942093-A COMPOSITES, THERMOSETTING RESINS, A BISMALEIMIDE COMPOUND AND AN ISOCYANATE TERMINATED RUBBER BONDED TO A POLYURETHANES, TIR ES BRIDGESTONE/FIRESTONE, INC. (US) 1990-07-17 US disclosed
EP-0358084-A2 An adhesive system for bonding uncured rubber to cured polyurethane BRIDGESTONE/FIRESTONE, INC. (US) 1990-03-14 EP disclosed
US-4555418-A LAMINATION THE CELOTEX CORPORATION (US) 1985-11-26 US disclosed
EP-0137489-A2 Polyisocyanurate foam prepared from an alkoxylated aromatic amine-aromatic polyester polyol blend THE CELOTEX CORPORATION (US) 1985-04-17 EP disclosed
US-4496625-A LAMINATES FOR ROOFING INSULATION; ADHESION; FIRE RESISTANCE; ELASTICITY; COMPRESSIVE STRENGTH THE CELOTEX CORPORATION (US) 1985-01-29 US disclosed
US-4066523-A DUAL CURE CATHODIC ELECTROCOATING COMPOSITION SCM CORPORATION (US) 1978-01-03 US disclosed
US-4025409-A Dual cure cathodic electrocoating process SCM CORPORATION (US) 1977-05-24 US disclosed