Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 12/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642635 | 0.81 | PIK3CD (0.42) | ACVRL1PIK3CD | |
| SCHEMBL14642738 | 0.81 | ACVRL1 (0.41) | ACVRL1PIK3CD | |
| SCHEMBL14642543 | 0.80 | ACVRL1 (0.37) | ACVRL1PIK3CD | |
| SCHEMBL14642597 | 0.80 | PIK3CD (0.38) | ACVRL1PIK3CD | |
| SCHEMBL14642529 | 0.77 | PIK3CD (0.37) | ACVRL1PIK3CD | |
| SCHEMBL7602186 | 0.77 | ACVRL1 (0.36) | ACVRL1PIK3CD | |
| SCHEMBL14642542 | 0.77 | CSNK2A2 (0.36) | ACVRL1PIK3CD | |
| SCHEMBL7600101 | 0.77 | ACVRL1 (0.41) | ACVRL1PIK3CD | |
| SCHEMBL13532224 | 0.75 | CSNK2A2 (0.38) | ACVRL1PIK3CD | |
| SCHEMBL9912350 | 0.74 | MAPK1 (0.36) | ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |