Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 13/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642542 | 0.89 | CSNK2A2 (0.36) | CSNK2A2CSNK2A1PIK3CDACVRL1NTRK1 | |
| SCHEMBL14642529 | 0.89 | PIK3CD (0.37) | CSNK2A2CSNK2A1PIK3CDACVRL1AXL | |
| SCHEMBL7602186 | 0.85 | ACVRL1 (0.36) | CSNK2A2CSNK2A1PIK3CDACVRL1 | |
| SCHEMBL14642543 | 0.82 | ACVRL1 (0.37) | PIK3CDACVRL1 | |
| SCHEMBL14642597 | 0.82 | PIK3CD (0.38) | PIK3CDACVRL1 | |
| SCHEMBL14642530 | 0.77 | ACVRL1 (0.36) | CSNK2A2CSNK2A1PIK3CDACVRL1RIPK1 | |
| SCHEMBL13519756 | 0.77 | ACVRL1 (0.36) | CSNK2A2CSNK2A1PIK3CDACVRL1AXL | |
| SCHEMBL9912315 | 0.77 | CSNK2A2 (0.34) | CSNK2A2CSNK2A1PIK3CDACVRL1AXL | |
| SCHEMBL14642635 | 0.76 | PIK3CD (0.42) | PIK3CDACVRL1 | |
| SCHEMBL14642738 | 0.76 | ACVRL1 (0.41) | PIK3CDACVRL1KDRTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100015094-A1 | ANTIVIRAL NUCLEOSIDE ANALOGS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015094-A1 | ANTIVIRAL NUCLEOSIDE ANALOGS | TYMP, SAMHD1, TYMS | CSNK2A2 3359/4885CSNK2A1 2946/4885PIK3CD 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.