Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 17/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.31 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.31 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.31 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101538 | 0.92 | ACVRL1 (0.37) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL645192 | 0.91 | ACVRL1 (0.38) | ACVRL1ADORA2AMTORRICTORRPTOR | |
| SCHEMBL13519794 | 0.91 | ACVRL1 (0.38) | ACVRL1ADORA2AMTORRICTORRPTOR | |
| SCHEMBL13519812 | 0.87 | ACVRL1 (0.37) | ACVRL1ADORA2AMTORRICTORRPTOR | |
| SCHEMBL10101537 | 0.86 | ACVRL1 (0.38) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL10101599 | 0.81 | ACVRL1 (0.38) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL10101535 | 0.81 | ACVRL1 (0.38) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL13519796 | 0.80 | ADK (0.40) | ACVRL1ADORA2A | |
| SCHEMBL13519791 | 0.78 | ADORA2A (0.34) | ACVRL1ADORA2A | |
| SCHEMBL14642816 | 0.77 | ACVRL1 (0.41) | ACVRL1MTORRICTORRPTORMAPKAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |