Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10100350 | 0.91 | HIF1A (0.41) | HIF1AACVRL1ADORA3ADORA2AADORA1 | |
| SCHEMBL10101576 | 0.89 | CSNK2A2 (0.34) | ACVRL1 | |
| SCHEMBL10101513 | 0.89 | CSNK2A2 (0.34) | ACVRL1 | |
| SCHEMBL10101575 | 0.86 | CSNK2A2 (0.34) | LGALS3HIF1AACVRL1ADORA3ADORA2A | |
| SCHEMBL10101582 | 0.81 | PIK3CD (0.34) | ACVRL1HSPA8 | |
| SCHEMBL10101512 | 0.81 | PIK3CD (0.34) | ACVRL1HSPA8 | |
| SCHEMBL13519792 | 0.81 | DOT1L (0.46) | HIF1AACVRL1ADORA3ADORA2AADORA1 | |
| SCHEMBL13519756 | 0.80 | ACVRL1 (0.36) | ACVRL1 | |
| SCHEMBL10101515 | 0.78 | ACVRL1 (0.33) | ACVRL1 | |
| SCHEMBL10101578 | 0.78 | KDM4E (0.36) | HIF1AACVRL1ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |