Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | GAPDH | P04406 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101575 | 0.91 | CSNK2A2 (0.34) | HIF1AGAPDHADORA3ADORA2ADOT1L | |
| SCHEMBL13519789 | 0.91 | LGALS3 (0.35) | HIF1AGAPDHADORA3ADORA2ADOT1L | |
| SCHEMBL10101576 | 0.83 | CSNK2A2 (0.34) | ACVRL1 | |
| SCHEMBL10101513 | 0.83 | CSNK2A2 (0.34) | ACVRL1 | |
| SCHEMBL10101578 | 0.82 | KDM4E (0.36) | HIF1AGAPDHADORA3ADORA2ADOT1L | |
| SCHEMBL13519808 | 0.79 | ADORA2A (0.41) | ADORA2AACVRL1 | |
| SCHEMBL647116 | 0.79 | ADORA2A (0.41) | ADORA2AACVRL1 | |
| SCHEMBL13519756 | 0.78 | ACVRL1 (0.36) | ACVRL1 | |
| SCHEMBL10101583 | 0.78 | NPC1 (0.40) | HIF1AGAPDHADORA3ADORA2ADOT1L | |
| SCHEMBL14642542 | 0.78 | CSNK2A2 (0.36) | ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114980-B1 | ANTIVIRAL NUCLEOSIDE ANALOGS | BIOCRYST PHARM INC (US) | 2012-06-27 | — | — | EP | disclosed |