Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601633 | 0.88 | KCNH2 (0.44) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL115123 | 0.82 | ADRB2 (0.54) | TOP2ATOP2BADRB2KCNH2ALDH1A1 | |
| SCHEMBL13944952 | 0.81 | KCNH2 (0.40) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL143295 | 0.80 | TOP2A (0.60) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL2601622 | 0.80 | KCNH2 (0.44) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL2108874 | 0.79 | KDM4E (0.49) | TOP2ATOP2BADRB2KCNH2GSK3B | |
| SCHEMBL2825321 | 0.78 | KCNH2 (0.45) | TOP2ATOP2BKCNH2GSK3BALDH1A1 | |
| SCHEMBL13945289 | 0.78 | ADRB2 (0.43) | TOP2ATOP2BADRB2KCNH2GSK3B | |
| SCHEMBL13315605 | 0.77 | KCNH2 (0.42) | TOP2ATOP2BADRB2KCNH2GSK3B | |
| SCHEMBL13315596 | 0.76 | ALDH1A1 (0.47) | TOP2ATOP2BADRB2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002415-A1 | TREATMENT OF ANTIBIOTIC-RESISTANT BACTERIA INFECTION | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-01-07 | — | — | WO | disclosed |
| WO-2009023473-A2 | ANTIMICROBIAL PARENTERAL FORMULATION | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-02-19 | — | — | WO | disclosed |