SCHEMBL13520751

SCHEMBL13520751

c1ccc(-c2ccc(-c3ccc(C(c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)c4cc5ccccc5c5ccccc45)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 2/20 0.42
PLA2G2A P14555 4/20 0.42
PLA2G4A P47712 4/20 0.42
KDM4E B2RXH2 4/20 0.38
HPGD P15428 4/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PLA2G10 O15496 1/20 0.38
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
GLA P06280 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CASP3 P42574 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13520875 0.95 NQO1 (0.39) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520753 0.87 NQO1 (0.34) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520689 0.86 NQO1 (0.43) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520670 0.86 NQO1 (0.43) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520686 0.85 PLA2G2A (0.51) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520667 0.85 PLA2G2A (0.51) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520716 0.85 PLA2G2A (0.51) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520722 0.85 PLA2G2A (0.51) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520765 0.85 PLA2G2A (0.51) NQO1PLA2G2APLA2G4AKDM4EHPGD
SCHEMBL13520677 0.85 PLA2G2A (0.43) NQO1PLA2G2APLA2G4AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100001636-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 NQO1 982/4885PLA2G2A 4139/4885PLA2G4A 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.