Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521904 | 0.88 | MAPK1 (0.38) | L3MBTL1ALDH1A1MAPTCYP1A2POLB | |
| SCHEMBL1011312 | 0.84 | PKM (0.40) | L3MBTL1ABL1RIN1CTSDALDH1A1 | |
| SCHEMBL349203 | 0.84 | CYP3A4 (0.40) | L3MBTL1ABL1RIN1CTSDALDH1A1 | |
| SCHEMBL349119 | 0.84 | CYP3A4 (0.55) | L3MBTL1ABL1RIN1CTSDALDH1A1 | |
| SCHEMBL2278005 | 0.83 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL13521899 | 0.83 | HTT (0.47) | ALDH1A1MAPTPOLBLMNAHTT | |
| SCHEMBL347866 | 0.83 | PPARG (0.52) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL349573 | 0.83 | CYP3A4 (0.45) | L3MBTL1ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL349505 | 0.82 | CYP3A4 (0.41) | L3MBTL1ABL1RIN1CTSDALDH1A1 | |
| SCHEMBL13521859 | 0.82 | ALDH1A1 (0.44) | CTSDALDH1A1MAPTGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003127-A2 | ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |