Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 17/20 | 0.53 |
| ▸ | NPY2R | P49146 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522166 | 0.96 | MTTP (0.54) | MTTPNPY2R | |
| SCHEMBL13522053 | 0.92 | MTTP (0.56) | MTTPNPY2R | |
| SCHEMBL12174381 | 0.90 | MTTP (0.61) | MTTPNPY2R | |
| SCHEMBL12174484 | 0.89 | MTTP (0.66) | MTTPNPY2R | |
| SCHEMBL13522149 | 0.88 | NPY2R (0.61) | MTTPNPY2R | |
| Trifluoroacetic Acid SCHEMBL2588248 | 0.88 | MTTP (0.59) | MTTPNPY2R | |
| SCHEMBL13522054 | 0.87 | NPY2R (0.54) | MTTPNPY2R | |
| SCHEMBL13522152 | 0.86 | NPY2R (0.53) | MTTPNPY2R | |
| SCHEMBL13522061 | 0.86 | MTTP (0.55) | MTTPNPY2R | |
| SCHEMBL12174380 | 0.86 | MTTP (0.56) | MTTPNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642378-B2 | Lipid lowering biphenylcarboxamides | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-05 | — | — | US | disclosed |
| US-7642378-B2 | Lipid lowering biphenylcarboxamides | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-05 | — | — | US | disclosed |
| US-20080081813-A1 | Lipid Lowering Biphenylcarboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-03 | — | — | US | disclosed |
| US-20080081813-A1 | Lipid Lowering Biphenylcarboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081813-A1 | Lipid Lowering Biphenylcarboxamides | LIPC, PNLIP, LIPA | MTTP 20/4885NPY2R 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.