Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630409 | 0.85 | HSP90AA1 (0.51) | HSP90AA1POLBALDH1A1MAPTKMT2A | |
| SCHEMBL1628566 | 0.82 | HSP90AA1 (0.49) | HSP90AA1KDM4APOLBMAPTKMT2A | |
| SCHEMBL13522938 | 0.81 | HSP90AA1 (0.51) | HSP90AA1POLBLMNAALDH1A1HPGD | |
| SCHEMBL13522940 | 0.81 | HSP90AA1 (0.51) | HSP90AA1KDM4APOLBLMNATSHR | |
| SCHEMBL13522939 | 0.81 | HSP90AA1 (0.51) | HSP90AA1POLBLMNATSHRHPGD | |
| SCHEMBL12722866 | 0.80 | HSP90AA1 (0.53) | HSP90AA1POLBLMNAALDH1A1KMT2A | |
| SCHEMBL1630238 | 0.79 | MAPT (0.51) | HSP90AA1TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL28840679 | 0.79 | POLB (0.47) | HSP90AA1POLBLMNATSHRALDH1A1 | |
| SCHEMBL6448933 | 0.78 | BCHE (0.46) | HSP90AA1KDM4AALDH1A1HPGDMAPT | |
| SCHEMBL625870 | 0.77 | HSP90AA1 (0.68) | HSP90AA1NR3C2IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |