Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522945 | 0.79 | HSP90AA1 (0.51) | POLBMDM2HSP90AA1ALDH1A1MAPT | |
| SCHEMBL1155787 | 0.75 | MDM2 (0.55) | POLBMDM2ALDH1A1HTTLMNA | |
| SCHEMBL1777078 | 0.75 | POLB (0.43) | POLBMDM2HSP90AA1ALDH1A1HTT | |
| SCHEMBL13522939 | 0.74 | HSP90AA1 (0.51) | POLBMDM2HSP90AA1MAPTSMN1; SMN2 | |
| SCHEMBL15202358 | 0.74 | COMT (0.43) | POLBALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29790460 | 0.74 | COMT (0.43) | POLBALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5318677 | 0.72 | POLB (0.57) | POLBMDM2ALDH1A1HTTMAPT | |
| SCHEMBL31276894 | 0.71 | NPC1 (0.53) | ALDH1A1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL1630409 | 0.71 | HSP90AA1 (0.51) | POLBMDM2HSP90AA1ALDH1A1MAPT | |
| SCHEMBL27325285 | 0.71 | MDM2 (0.46) | POLBMDM2HSP90AA1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907404-B | 5- (2- (Disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolyl phosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-114907404-A | 5- (2- (disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolylphosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2022-08-16 | — | — | CN | disclosed |