Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.40 |
| ▸ | KDM5A | P29375 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522945 | 0.78 | HSP90AA1 (0.51) | ALDH1A1HPGDHSD17B10KDM5AHSP90AA1 | |
| SCHEMBL6450478 | 0.77 | PDCD1 (0.49) | BCHEACHEBACE1ALDH1A1HPGD | |
| SCHEMBL22349328 | 0.76 | KDM5A (0.59) | BCHEACHEBACE1KDM4CKDM5B | |
| SCHEMBL6448862 | 0.76 | ALDH1A1 (0.46) | BCHEACHEBACE1ALDH1A1HPGD | |
| SCHEMBL9697055 | 0.75 | RAB9A (0.44) | BCHEACHEBACE1ALDH1A1HPGD | |
| SCHEMBL3359356 | 0.74 | GRM4 (0.56) | ALDH1A1HPGDHSD17B10KDM4CKDM5B | |
| SCHEMBL625870 | 0.73 | HSP90AA1 (0.68) | HSP90AA1IDO1KDM4E | |
| SCHEMBL17086621 | 0.71 | KDM4C (0.57) | ACHEBACE1ALDH1A1HSD17B10KDM4C | |
| SCHEMBL6449004 | 0.71 | GRM5 (0.50) | BCHEACHEBACE1ALDH1A1HPGD | |
| SCHEMBL6452314 | 0.71 | ALDH1A1 (0.47) | BCHEACHEBACE1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | BCHE 773/4885ACHE 2052/4885BACE1 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.