Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.80 |
| ▸ | KIT | P10721 | 11/20 | 0.80 |
| ▸ | FLT3 | P36888 | 11/20 | 0.80 |
| ▸ | CSF1R | P07333 | 7/20 | 0.80 |
| ▸ | FLT1 | P17948 | 7/20 | 0.80 |
| ▸ | FLT4 | P35916 | 6/20 | 0.80 |
| ▸ | FYN | P06241 | 5/20 | 0.80 |
| ▸ | LYN | P07948 | 5/20 | 0.80 |
| ▸ | BLK | P51451 | 5/20 | 0.80 |
| ▸ | SRC | P12931 | 4/20 | 0.80 |
| ▸ | LCK | P06239 | 4/20 | 0.80 |
| ▸ | ABL1 | P00519 | 3/20 | 0.80 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.58 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.58 |
| ▸ | MARK2 | Q7KZI7 | 3/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.58 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.58 |
| ▸ | AXL | P30530 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421748 | 0.89 | KDR (1.00) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL13523211 | 0.87 | KDR (0.80) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL422687 | 0.80 | KDR (0.79) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL420194 | 0.80 | KDR (0.80) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL421150 | 0.78 | KDR (0.79) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL425258 | 0.77 | KDR (0.82) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL424599 | 0.77 | KDR (0.84) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL424715 | 0.77 | KDR (1.00) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL13523213 | 0.77 | KDR (0.81) | KDRKITFLT3CSF1RFLT1 | |
| SCHEMBL422629 | 0.77 | KDR (0.75) | KDRKITFLT3CSF1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004306-A1 | PIGF-1 Assay and kits and components thereof | ABBOTT LABORATORIES (US) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004306-A1 | PIGF-1 Assay and kits and components thereof | PGF, FLT1, HDGF | KDR 9/4885KIT 140/4885FLT3 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.