Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199895 | 0.74 | NOS3 (0.59) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL5958858 | 0.74 | NOS3 (0.59) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL13523420 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL2075410 | 0.73 | NOS3 (1.00) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL2230501 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL30681225 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL2127063 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL14153565 | 0.73 | NOS3 (0.57) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL688175 | 0.72 | NOS3 (0.56) | NOS3NOS1NOS2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8324907 | 0.71 | NOS3 (0.96) | NOS3NOS1NOS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215093-B1 | NOVEL PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20100001635-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2010-01-07 | — | — | US | disclosed |
| EP-2108690-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-10-14 | — | — | EP | disclosed |
| US-20090200926-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-08-13 | — | — | US | disclosed |
| EP-2075309-A2 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-07-01 | — | — | EP | disclosed |
| EP-2067767-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100001635-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | ORMDL3, ILF2, L1CAM | NOS3 401/4885NOS1 66/4885NOS2 43/4885 |
| US-20090200926-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | NQO1, NDUFS2, NDUFS5 | NOS3 661/4885NOS1 191/4885NOS2 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.