Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 7/20 | 0.47 |
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253118 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL14430275 | 0.81 | CYP3A4 (0.68) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL5680616 | 0.80 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL5920334 | 0.80 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL5921414 | 0.80 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL5678389 | 0.80 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL6635785 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL3620867 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL11524101 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9THRBTHRA | |
| SCHEMBL5919910 | 0.75 | CYP2C9 (0.49) | CYP3A4CYP2D6CYP2C9THRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | CYP3A4 1324/4885CYP2D6 873/4885CYP2C9 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.