Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635785 | 1.00 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL11524101 | 1.00 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL10346503 | 0.96 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL12416611 | 0.96 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL1129722 | 0.95 | CYP2C9 (0.55) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL1129724 | 0.95 | CYP2C9 (0.55) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL5665735 | 0.93 | CYP3A4 (0.54) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL5665730 | 0.93 | CYP3A4 (0.54) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL12416633 | 0.93 | CYP3A4 (0.62) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B | |
| SCHEMBL3623036 | 0.93 | CYP3A4 (0.62) | CYP3A4CYP2D6CYP2C9GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835456-B2 | Base polymer of a polyamide having pendant hydroxyl groups or polybenzoxazole and as dye component methine dyes, azomethine dyes, coumarin dyes, triarylmethane dyes and/or azo dyes and their derivatives; ARC coatings (antireflective coatings) | INFINEON TECHNOLOGIES AG (DE) | 2004-12-28 | — | — | US | claimed |
| US-20020198294-A1 | Antireflective, layer-forming composition, layer configuration containing the antireflective layer, and process for producing the antireflective layer | POLARIS INNOVATIONS LIMITED (IE) | 2002-12-26 | — | — | US | claimed |
| US-10996496-B2 | Composite film, device including, and method of forming the same | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-05-04 | — | — | US | disclosed |
| EP-3500890-A1 | COMPOSITE FILM, DEVICE INCLUDING, AND METHOD OF FORMING THE SAME | Nanyang Technological University (SG) | 2019-06-26 | — | — | EP | disclosed |
| US-20190179176-A1 | COMPOSITE FILM, DEVICE INCLUDING, AND METHOD OF FORMING THE SAME | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2019-06-13 | — | — | US | disclosed |
| EP-2799516-B1 | LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF | HALATION PHOTONICS CORP (CN) | 2019-02-20 | — | — | EP | disclosed |
| US-9175220-B2 | High scattering smectic liquid crystal material and display device using the same | HALATION PHOTONICS CORPORATION (CN) | 2015-11-03 | — | — | US | disclosed |
| US-9175220-B2 | High scattering smectic liquid crystal material and display device using the same | HALATION PHOTONICS CORPORATION (CN) | 2015-11-03 | — | — | US | disclosed |
| US-20100302487-A1 | PHASE COMPENSATION FILM | DOW GLOBAL TECHNOLOGIES LLC | 2010-12-02 | — | — | US | disclosed |
| US-20100294989-A1 | SMALL SCALE FUNCTIONAL MATERIALS | DOW GLOBAL TECHNOLOGIES LLC | 2010-11-25 | — | — | US | disclosed |
| EP-2231760-A1 | SMALL SCALE FUNCTIONAL MATERIALS | Dow Global Technologies Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20020045628-A1 | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-04-18 | — | — | US | disclosed |
| US-6313126-B1 | FOR THRERAPY OF DISORDERS ASSOCIATED WITH DYSFUNCTION IN SEROTONERGIC NEUROTRANSMISSION, INCLUDING DEPRESSION AND ANXIETY | AMERICAN HOME PRODUCTS CORP | 2001-11-06 | — | — | US | disclosed |
| EP-1147083-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000040554-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-13 | — | — | WO | disclosed |
| US-5068052-A | Polyoxymethylene resin and liquid crystal polyester for films or fibers | POLYPLASTICS CO., LTD. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0106175-B1 | ELECTRICALLY CONDUCTIVE LIQUID CRYSTALLINE SUBSTANCE AND POLYMER | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4769448-A | CHARGE TRANSFER COMPOUNDS | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1988-09-06 | — | — | US | disclosed |
| US-4657694-A | CONTAINING A CHARGE TRANSFER COMPOUND | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0106175-A2 | Electrically conductive liquid crystalline substance and polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045628-A1 | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | HTR2C, TPH1, TPH2 | CYP3A4 410/4885CYP2D6 278/4885CYP2C9 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.