Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525206 | 0.76 | TXNRD1 (0.57) | GAALMNAMAPTMPIHTT | |
| SCHEMBL13525196 | 0.74 | CA12 (0.41) | GAALMNAMAPTMPIHTT | |
| SCHEMBL7593877 | 0.74 | — | — | |
| SCHEMBL13525239 | 0.74 | CA1 (0.38) | HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL13010086 | 0.74 | AGTR1 (0.39) | GAALMNAMAPTMPIHTT | |
| SCHEMBL13525187 | 0.72 | GAA (0.35) | GAALMNAMAPTMPIHTT | |
| SCHEMBL13525236 | 0.71 | MAPT (0.38) | GAALMNAMAPTMPIHTT | |
| SCHEMBL13525189 | 0.70 | CYP3A4 (0.42) | GAALMNAMAPTMPIHTT | |
| SCHEMBL1435819 | 0.69 | KDM4E (0.33) | GAAALDH1A1 | |
| SCHEMBL11241480 | 0.69 | CA1 (0.33) | HTTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | KRT18, IK, KLK5 | GAA 3924/4885LMNA 1287/4885MAPT 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.