Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015730 | 0.81 | BACE1 (0.49) | POLBMAPTKDM4EBACE1TDP1 | |
| SCHEMBL14682218 | 0.81 | BACE1 (0.49) | POLBMAPTKDM4EBACE1TDP1 | |
| SCHEMBL13986166 | 0.81 | BACE1 (0.49) | POLBMAPTKDM4EBACE1TDP1 | |
| SCHEMBL15417137 | 0.81 | BACE1 (0.49) | POLBMAPTKDM4EBACE1TDP1 | |
| SCHEMBL12960520 | 0.79 | ELANE (0.45) | POLBMAPTHTTKDM4EBACE1 | |
| SCHEMBL3365404 | 0.79 | KDR (0.56) | MAPTHTTEDNRAKDM4ETSPO | |
| SCHEMBL760421 | 0.78 | NPSR1 (0.54) | POLBMAPTHTTKDM4EBACE1 | |
| SCHEMBL16488964 | 0.78 | HSD17B10 (0.53) | POLBMAPTKDM4EBACE1TDP1 | |
| SCHEMBL12603929 | 0.78 | LMNA (0.47) | POLBMAPTBACE1TDP1LMNA | |
| SCHEMBL13779223 | 0.77 | BACE1 (0.46) | POLBMAPTBACE1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652126-B2 | Bisphenol having conjugated aromatic functionality; active materials for electrooptical and electroluminescent devices; polymerization; economic, high yield | GENERAL ELECTRIC COMPANY (US) | 2010-01-26 | — | — | US | disclosed |