SCHEMBL13986166

SCHEMBL13986166

COc1ccc(-c2ccc(OC(=O)Oc3ccc(C(C)(C)c4ccc(OC(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.49
HSD17B10 Q99714 3/20 0.49
LMNA P02545 3/20 0.43
MAPT P10636 5/20 0.42
GAA P10253 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
ESR2 Q92731 1/20 0.41
ELANE P08246 1/20 0.41
MEN1 O00255 2/20 0.40
PKM P14618 2/20 0.40
KMT2A Q03164 2/20 0.40
MDM2 Q00987 1/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15417137 1.00 BACE1 (0.49) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL10015730 1.00 BACE1 (0.49) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL14682218 1.00 BACE1 (0.49) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL12603929 0.95 LMNA (0.47) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL16488964 0.95 HSD17B10 (0.53) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL12890391 0.91 ELANE (0.45) BACE1HSD17B10LMNAMAPTALDH1A1
SCHEMBL13712362 0.91 LMNA (0.52) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL800223 0.91 LMNA (0.52) BACE1HSD17B10LMNAMAPTGAA
SCHEMBL13986167 0.90 ELANE (0.54) HSD17B10LMNAMAPTGAAALDH1A1
SCHEMBL13415738 0.89 HSD17B10 (0.50) HSD17B10LMNAMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9618881-B2 Biaryl polycarbonate intermediate transfer members XEROX CORPORATION (US) 2017-04-11 US disclosed
US-20150261105-A1 BIPHENYL POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-09-17 US disclosed
US-20140079446-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2014-03-20 US disclosed
US-20130034733-A1 BIARYL POLYCARBONATE INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-02-07 US disclosed
US-7468230-B2 Wet-developing electrophotographic photoconductor and wet-developing image KYOCERA MITA CORPORATION (JP) 2008-12-23 US disclosed