Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51705 | 0.85 | POLB (0.61) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL27297772 | 0.84 | POLB (0.65) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL1638977 | 0.83 | GAA (0.52) | POLBNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2045876 | 0.83 | POLB (0.64) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL2061056 | 0.83 | KDM4E (0.50) | POLBESR1CYP19A1ESR2ALDH1A1 | |
| SCHEMBL639120 | 0.82 | POLB (0.57) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL3210936 | 0.82 | POLB (0.57) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL22284798 | 0.82 | POLB (0.57) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL639119 | 0.82 | POLB (0.57) | POLBESR1CYP19A1ESR2NPC1 | |
| SCHEMBL2290549 | 0.82 | KDM4E (0.46) | POLBESR1CYP19A1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664330-B2 | Reactive hot melt adhesive with improved hydrolysis resistance | Henkel US IP LLC (US) | 2014-03-04 | — | — | US | claimed |
| US-7037402-B2 | Reactive hot melt adhesive with non-polymeric aromatic difunctionals | NATIONAL STARCH & CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2006-05-02 | — | — | US | claimed |
| WO-2004035706-A1 | REACTIVE HOT MELT ADHESIVE WITH NON-POLYMERIC AROMATIC DIFUNCTIONALS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING C ORPORATION (US) | 2004-04-29 | — | — | WO | claimed |
| US-20040072952-A1 | Reactive hot melt adhesive with non-polymeric aromatic difunctionals | HENKEL AG & CO. KGAA (DE) | 2004-04-15 | — | — | US | claimed |
| US-20230341775-A1 | CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| CN-113816985-B | Twin monomer containing cationic polymerizable group and preparation method and application thereof | 同济大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113816985-A | Twin monomer containing cationic polymerizable group and preparation method and application thereof | 同济大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-107011131-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-11-10 | — | — | CN | disclosed |
| CN-107011132-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-11-10 | — | — | CN | disclosed |
| EP-2612845-B1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | AJINOMOTO KK (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10711033-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| CN-106220482-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-01-07 | — | — | CN | disclosed |
| CN-1468102-A | Modified prodrug forms of ap/amp | ά�¶�ҩƷ��˾ | 2004-01-14 | — | — | CN | disclosed |
| EP-1335726-A1 | MODIFIED PRODRUG FORMS OF AP/AMP | Vion Pharmaceuticals, Inc. (US) | 2003-08-20 | — | — | EP | disclosed |
| US-20020188011-A1 | Antiviral agents and methods of treating viral infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-12-12 | — | — | US | disclosed |
| WO-2002085358-A2 | ANTIVIRAL AGENTS AND METHODS OF TREATING VIRAL INFECTIONS | VION PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6458816-B1 | ANTICANCER AGENTS | VION PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-20020119955-A1 | Modified prodrug forms of AP/AMP | NANOTHERAPEUTICS, INC. | 2002-08-29 | — | — | US | disclosed |
| WO-2002030424-A1 | MODIFIED PRODRUG FORMS OF AP/AMP | VION PHARMACEUTICALS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| US-4025553-A | Production of o-hydroxybenzyl alcohols | SHIONOGI & CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188011-A1 | Antiviral agents and methods of treating viral infections | AMPD3, AMPD2, MTAP | POLB 960/4885ESR1 4822/4885CYP19A1 4648/4885 |
| US-10711033-B2 | Branched chain-containing aromatic compound | VIP, IAPP, BCAT1 | POLB 3426/4885ESR1 3642/4885CYP19A1 1967/4885 |
| US-20020119955-A1 | Modified prodrug forms of AP/AMP | AP3B1, AP3D1, AP3M1 | POLB 1211/4885ESR1 2480/4885CYP19A1 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.