Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655549 | 0.80 | RAB9A (0.57) | LMNAPOLBHDAC3HDAC1HDAC8 | |
| SCHEMBL13655565 | 0.80 | NPC1 (0.56) | LMNAPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL15298855 | 0.80 | SCN1A (0.46) | SCN1ASCN2ASCN3ALMNAPOLB | |
| SCHEMBL24419849 | 0.80 | SCN1A (0.46) | SCN1ASCN2ASCN3ALMNAPOLB | |
| SCHEMBL13527116 | 0.78 | MAPT (0.59) | LMNAPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL16506627 | 0.78 | NPC1 (0.44) | SCN1ASCN2ASCN3ALMNAHDAC3 | |
| SCHEMBL19941397 | 0.77 | KDM4E (0.57) | SCN1ASCN2ASCN3ALMNAPOLB | |
| SCHEMBL25390106 | 0.77 | SCN1A (0.71) | SCN1ASCN2ASCN3ALMNAPOLB | |
| SCHEMBL24209234 | 0.76 | SCN1A (0.57) | SCN1ASCN2ASCN3AHDAC3HDAC1 | |
| SCHEMBL13655557 | 0.76 | HDAC3 (0.56) | SCN1ASCN2ASCN3AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2012-10-04 | — | — | US | disclosed |
| US-20100016955-A1 | Triazole compounds and methods of making and using the same | BioVersys AG (CH) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016955-A1 | Triazole compounds and methods of making and using the same | IL33, PROKR1, VIP | SCN1A 4868/4885SCN2A 4873/4885SCN3A 4611/4885 |
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CCNO, PTGDR, CCNE1 | SCN1A 3468/4885SCN2A 3990/4885SCN3A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.