Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291499 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5303135 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5292618 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5299807 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5288471 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5289119 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5287955 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5286315 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5308719 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 | |
| SCHEMBL5819599 | 0.96 | KMT2A (0.67) | KMT2AMEN1MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143928-A1 | BIS-PYRINIDIUM COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2013-06-06 | — | — | US | disclosed |
| US-20100016367-A1 | BIS-PYRINIDIUM COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016367-A1 | BIS-PYRINIDIUM COMPOUNDS | PNPO, DHFR, PLPBP | KMT2A 3208/4885MEN1 959/4885MAPT 1076/4885 |
| US-20130143928-A1 | BIS-PYRINIDIUM COMPOUNDS | PNPO, DHFR, PLPBP | KMT2A 3208/4885MEN1 959/4885MAPT 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.