Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527791 | 0.93 | HDAC1 (0.43) | ADRB2HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL30941341 | 0.79 | PPARG (0.39) | ADRB2SSTR4 | |
| SCHEMBL31618007 | 0.79 | L3MBTL1 (0.41) | HDAC1HDAC3HDAC2NCOR2AKT1 | |
| SCHEMBL22032132 | 0.78 | ADRB2 (0.47) | ADRB2HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL16329450 | 0.77 | HDAC3 (0.44) | HDAC1HDAC3HDAC2NCOR2AKT1 | |
| SCHEMBL21391234 | 0.77 | HDAC1 (0.45) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL31617927 | 0.76 | PPARG (0.43) | ADRB2 | |
| SCHEMBL15567660 | 0.76 | HDAC3 (0.40) | HDAC1HDAC3HDAC2NCOR2FOLH1 | |
| SCHEMBL14270324 | 0.75 | HDAC3 (0.37) | ADRB2HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL14270224 | 0.75 | HDAC3 (0.37) | ADRB2HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | DYNLL2, ATXN2L, DYNLL1 | ADRB2 3285/4885HDAC1 2550/4885HDAC3 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.