SCHEMBL135279

SCHEMBL135279

CC1(C)C(/C=C/Nc2ccccc2)=[N+](CCCS(=O)(=O)[O-])c2ccc(CN3C(=O)c4ccccc4C3=O)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
MMP14 P50281 1/20 0.38
PRMT1 Q99873 3/20 0.35
BLM P54132 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
HRH2 P25021 6/20 0.33
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134567 0.81 CA12 (0.40) MEN1KMT2AMAPTTHRBLMNA
SCHEMBL135730 0.80 MEN1 (0.42) MEN1KMT2AUSP2POLBMAPT
SCHEMBL5697854 0.76 PTPN1 (0.40) MEN1KMT2APOLBLMNAHTT
SCHEMBL5697851 0.76 PTPN1 (0.40) MEN1KMT2APOLBLMNAHTT
SCHEMBL136048 0.75 MEN1 (0.39) MEN1KMT2AUSP2POLBMAPT
SCHEMBL14812066 0.75 MEN1 (0.39) MEN1KMT2AUSP2POLBMAPT
SCHEMBL13567272 0.75 MEN1 (0.43) MEN1KMT2AUSP2POLBMAPT
SCHEMBL1656266 0.75 MEN1 (0.43) MEN1KMT2AUSP2POLBMAPT
SCHEMBL1714460 0.74 PRMT1 (0.45) MEN1KMT2AUSP2POLBMAPT
SCHEMBL1714462 0.74 PRMT1 (0.45) MEN1KMT2AUSP2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920365-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2018-03-20 US disclosed
US-20150344950-A1 Functionalized Cyanine Dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-12-03 US disclosed
US-9051263-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-06-09 US disclosed
US-8669374-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2014-03-11 US disclosed
US-20120058469-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US disclosed
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) ACR, IK, EGFR MEN1 3947/4885KMT2A 3543/4885USP2 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.