Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 6/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812066 | 1.00 | MEN1 (0.39) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL135730 | 0.94 | MEN1 (0.42) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL14823547 | 0.92 | PTPN1 (0.41) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL1715260 | 0.86 | HRH2 (0.42) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL1715259 | 0.86 | HRH2 (0.42) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL1714460 | 0.86 | PRMT1 (0.45) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL1714462 | 0.86 | PRMT1 (0.45) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL19976535 | 0.85 | MEN1 (0.40) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL136715 | 0.83 | BLM (0.43) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL1658645 | 0.82 | PTPN1 (0.41) | MEN1KMT2APOLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2024-04-25 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-9738786-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-08-22 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| EP-2758475-B1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20160355683-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150274976-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-10-01 | — | — | US | disclosed |
| US-9085698-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| US-9051263-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140323741-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD. (GB) | 2014-10-30 | — | — | US | disclosed |
| US-8669374-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2014-03-11 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885POLB 4597/4885 |
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885POLB 4597/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885POLB 4597/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885POLB 4597/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885KMT2A 2564/4885POLB 4597/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | MEN1 3947/4885KMT2A 3543/4885POLB 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.