Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1352862 | 1.00 | TSHR (0.37) | TSHRALDH1A1BACE1GRIK1GRIK2 | |
| SCHEMBL2535782 | 0.82 | — | — | |
| SCHEMBL21462991 | 0.82 | TSHR (0.30) | TSHRALDH1A1 | |
| SCHEMBL21462990 | 0.82 | TSHR (0.30) | TSHRALDH1A1 | |
| SCHEMBL2535783 | 0.82 | — | — | |
| SCHEMBL6752709 | 0.82 | — | — | |
| SCHEMBL6752710 | 0.82 | — | — | |
| SCHEMBL20018403 | 0.80 | — | — | |
| SCHEMBL6722403 | 0.80 | — | — | |
| SCHEMBL6722404 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102224146-B | Method for manufacturing sulfolene compound and method for manufacturing sulfolane compound | SUMITOMO SEIKA CHEMICALS | 2015-04-22 | — | — | CN | disclosed |
| EP-2368888-B1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-8436193-B2 | Method for manufacturing sulfolene compound and method for manufacturing sulfolane compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| CN-102224146-A | Method for manufacturing sulfolene compound and method for manufacturing sulfolane compound | SUMITOMO SEIKA CHEMICALS | 2011-10-19 | — | — | CN | disclosed |
| EP-2368888-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | Sumitomo Seika Chemicals CO. LTD. (JP) | 2011-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288307-A1 | METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND | SULT1A1, STS, SULT2A1 | TSHR 1420/4885ALDH1A1 43/4885BACE1 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.