SCHEMBL13528883

SCHEMBL13528883

CCCCCN1C(=O)O/C(=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GPR35 Q9HC97 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13109205 0.87 KMT2A (0.55) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL1104316 0.86 ALDH1A1 (0.49) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL31469813 0.84 GSK3A (0.42) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL13070217 0.84 GSK3A (0.42) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL1104345 0.84 GSK3A (0.42) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL13635924 0.83 KMT2A (0.36) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL12535545 0.81 MAPT (0.46) MEN1KMT2ANPC1RAB9AGPR35
SCHEMBL4544732 0.79 ALDH1A1 (0.49) ALDH1A1KDM4ESMN1; SMN2MAPTL3MBTL1
SCHEMBL14408420 0.79 ALDH1A1 (0.49) ALDH1A1KDM4ESMN1; SMN2MAPTL3MBTL1
SCHEMBL6752028 0.79 ALDH1A1 (0.47) MEN1KMT2ANPC1RAB9AGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1939687-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-09-14 EP disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
US-7618762-B2 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-7618762-B2 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-20080199804-A1 Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080199804-A1 Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080182205-A1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same KUNITA KAZUTO 2008-07-31 US disclosed
US-20080182205-A1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same KUNITA KAZUTO 2008-07-31 US disclosed