SCHEMBL4544732

SCHEMBL4544732

COc1ccc(CCN2C(=O)O/C(=C/c3ccc(N(c4ccccc4)c4ccccc4)cc3)C2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
LMNA P02545 2/20 0.49
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45
MAPT P10636 4/20 0.43
APP P05067 2/20 0.43
SNCA P37840 2/20 0.43
EP300 Q09472 1/20 0.43
ACHE P22303 1/20 0.41
KDM4E B2RXH2 2/20 0.41
PARK7 Q99497 1/20 0.40
PIM1 P11309 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
MAOB P27338 1/20 0.39
HSD17B3 P37058 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14408420 1.00 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2LMNAGSK3AGSK3B
SCHEMBL6752028 0.91 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2LMNAMAPTPIM1
SCHEMBL1104343 0.90 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2LMNAEP300PARK7
SCHEMBL31469813 0.89 GSK3A (0.42) ALDH1A1SMN1; SMN2GSK3AGSK3BMAPT
SCHEMBL1104345 0.89 GSK3A (0.42) ALDH1A1SMN1; SMN2GSK3AGSK3BMAPT
SCHEMBL13070217 0.89 GSK3A (0.42) ALDH1A1SMN1; SMN2GSK3AGSK3BMAPT
SCHEMBL14589284 0.89 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2LMNAGSK3AGSK3B
SCHEMBL14589315 0.88 MEN1 (0.38) ALDH1A1SMN1; SMN2LMNAMAPTACHE
SCHEMBL14589311 0.86 MAPT (0.39) ALDH1A1SMN1; SMN2LMNAMAPTPIM1
SCHEMBL14589304 0.86 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2LMNAMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
EP-1767995-B1 Method of producing photosensitive planographic printing plate precursor FUJIFILM CORP (JP) 2014-01-22 EP disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20110146516-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-23 US disclosed
US-20070059643-A1 Method of producing photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
EP-1762896-A2 Method of producing photosensitive planographic printing plate FUJIFILM Corporation (JP) 2007-03-14 EP disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070039500-A1 Manufacturing method of lithographic printing plate and manufacturing apparatus of lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
US-20070039500-A1 Manufacturing method of lithographic printing plate and manufacturing apparatus of lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
US-7169529-B2 Compound, photosensitive composition, lithographic printing plate precursor, and method of forming image FUJI PHOTO FILM CO., LTD. (JP) 2007-01-30 US disclosed
US-7169529-B2 Compound, photosensitive composition, lithographic printing plate precursor, and method of forming image FUJI PHOTO FILM CO., LTD. (JP) 2007-01-30 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER SORT1, ELOVL6, SCD5 ALDH1A1 2027/4885SMN1; SMN2 1252/4885LMNA 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.