SCHEMBL135305

SCHEMBL135305

O=C(O)CCN1C(=O)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.66
CA9 Q16790 1/20 0.66
NPSR1 Q6W5P4 1/20 0.65
POLB P06746 1/20 0.61
ALDH1A1 P00352 4/20 0.58
KMT2A Q03164 3/20 0.58
HSD17B10 Q99714 3/20 0.58
GAA P10253 1/20 0.58
HPGD P15428 1/20 0.58
MEN1 O00255 1/20 0.58
PKM P14618 1/20 0.57
ALOX15 P16050 2/20 0.56
TSHR P16473 2/20 0.56
KDM4E B2RXH2 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
SIRT1 Q96EB6 1/20 0.56
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30098360 1.00 CA12 (0.66) CA12CA9NPSR1POLBALDH1A1
SCHEMBL877279 0.89 KMT2A (0.73) CA12CA9ALDH1A1KMT2AHSD17B10
SCHEMBL29459522 0.89 KMT2A (0.73) CA12CA9ALDH1A1KMT2AHSD17B10
SCHEMBL13537849 0.88 CA12 (0.56) CA12CA9NPSR1POLBALDH1A1
SCHEMBL5371377 0.88 CA12 (0.56) CA12CA9NPSR1POLBALDH1A1
SCHEMBL1795851 0.87 HDAC8 (0.67) CA12CA9ALDH1A1KMT2AHSD17B10
Hydrochloric Acid SCHEMBL9878928 0.87 KMT2A (0.71) CA12CA9ALDH1A1KMT2AHSD17B10
SCHEMBL14594063 0.86 KMT2A (0.60) CA12CA9POLBALDH1A1KMT2A
SCHEMBL3468927 0.85 HDAC8 (0.69) ALDH1A1KMT2AHSD17B10GAAHPGD
SCHEMBL9899475 0.85 HDAC8 (0.69) ALDH1A1KMT2AHSD17B10GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530786-A Film stripping liquid suitable for flexible circuit board and preparation method thereof 深圳市天熙科技开发有限公司 2024-08-23 CN claimed
CN-114213503-A Synthesis method of snake venom-like tripeptide 上海予利生物科技股份有限公司 2022-03-22 CN claimed
CN-108070279-B Pigment dispersion and coloring composition using phthalimide and derivative thereof 山阳色素株式会社 2021-09-07 CN claimed
EP-2699557-B1 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS BIOTA SCIENT MANAGEMENT (AU) 2017-08-16 EP claimed
EP-1477486-A2 Imides as inhibitors of TNF alpha CELGENE CORPORATION (US) 2004-11-17 EP claimed
US-RE32868-E Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1989-02-14 US claimed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US claimed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4605088-A1 MOLECULAR GLUE DEGRADER COMPOUNDS AND USES THEREOF Novartis AG (CH) 2025-08-27 EP disclosed
US-20250059184-A1 IMIDAZOPYRIDINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2025-02-20 US disclosed
WO-2025021666-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-30 WO disclosed
CN-119320809-A Method for preparing L-carnosine by using yeast whole-cell catalyst 大连理工大学 2025-01-17 CN disclosed
US-20240425517-A1 NOVEL COMPOUND FOR DEGRADATION OF TARGET PROTEIN OR POLYPEPTIDE BY POLYUBIQUITINATION PRAZER THERAPEUTICS INC. (KR) 2024-12-26 US disclosed
US-4267174-A AND PROCESS FOR ADMINISTERING BOEHRINGER MANNHEIM, GMBH (DE) 1981-05-12 US disclosed
US-4230715-A 1,2,4-Triazole-3-thiols as antisecretory agents RICHARDSON-MERRELL INC. (US) 1980-10-28 US disclosed
US-4099010-A PHTHALOYL AMINO ACID HYDROXAMIC ACIDS MORTON-NORWICH PRODUCTS, INC. (US) 1978-07-04 US disclosed
US-4077998-A Phthaloyl amino acid hydroxamic acids MORTON-NORWICH PRODUCTS, INC. (US) 1978-03-07 US disclosed
US-4075221-A ALKYLATION WITH DIALKYLMETHYLENEAMMONIUM SALT IN PRESENCE OF REACTIVE CARBOXYLIC ACYLATING AGENT THE UPJOHN COMPANY (US) 1978-02-21 US disclosed
US-4012413-A 1-(2-AMINOALKYL)-6-PHENYL-TRIAZOLO-BENZODIAZEPINE COMPOUNDS USED AS TRANQUILIZERS AND ANTIDEPRESSANTS THE UPJOHN COMPANY (US) 1977-03-15 US disclosed
US-3994940-A Preparation of 1-(2-(dimethylamino)ethyl)-6-phenyl-4H-5-triazolo(4,3-a)(1,4)benzodiazepines THE UPJOHN COMPANY (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425517-A1 NOVEL COMPOUND FOR DEGRADATION OF TARGET PROTEIN OR POLYPEPTIDE BY POLYUBIQUITINATION ADRM1, SUMO1, SUMO2 CA12 4281/4885CA9 4354/4885NPSR1 3535/4885
US-20250059184-A1 IMIDAZOPYRIDINE PSYCHOPLASTOGENS AND USES THEREOF GRIN2A, GAP43, GRIN2C CA12 4439/4885CA9 4804/4885NPSR1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.