SCHEMBL877279

SCHEMBL877279

O=C(O)CCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.73
MEN1 O00255 3/20 0.73
HSD17B10 Q99714 3/20 0.67
GAA P10253 1/20 0.67
CASP1 P29466 1/20 0.67
CA12 O43570 1/20 0.61
CA9 Q16790 1/20 0.61
ALDH1A1 P00352 2/20 0.60
ACHE P22303 1/20 0.60
HDAC8 Q9BY41 3/20 0.59
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC7 Q8WUI4 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC10 Q969S8 2/20 0.59
HDAC11 Q96DB2 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
HDAC9 Q9UKV0 2/20 0.59
HDAC5 Q9UQL6 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459522 1.00 KMT2A (0.73) KMT2AMEN1HSD17B10GAACASP1
Hydrochloric Acid SCHEMBL9878928 0.98 KMT2A (0.71) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL1795851 0.95 HDAC8 (0.67) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL133529 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL9130049 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL607631 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL9350109 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL4202491 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL3468449 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1
SCHEMBL9899475 0.93 HDAC8 (0.69) KMT2AMEN1HSD17B10GAACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699557-B1 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS BIOTA SCIENT MANAGEMENT (AU) 2017-08-16 EP claimed
EP-2483283-B1 Method for the manufacture of aminohydroxy diphosphonic acids STRAITMARK HOLDING AG (CH) 2015-01-07 EP claimed
US-8779135-B2 Method for the manufacture of aminohydroxy diphosphonic acids STRAITMARK HOLDING AG (CH) 2014-07-15 US claimed
US-20120245354-A1 METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS STRAITMARK HOLDING AG (CH) 2012-09-27 US claimed
EP-2483283-A1 METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS Straitmark Holding AG (CH) 2012-08-08 EP claimed
EP-1477486-A2 Imides as inhibitors of TNF alpha CELGENE CORPORATION (US) 2004-11-17 EP claimed
EP-0792893-B1 Polyolefins modified with an unsaturated polyfunctional monomer containing an imide group and an ester group POLIMERI EUROPA SPA (IT) 2002-07-17 EP claimed
CN-1308627-A 11-Aryl-benzo[b]naphtho[2,3-d]furans and 11-aryl-aryl-benzo[b]anphtho[2,3-d]thiophenes useful in the treatment of insulin resistance and hyperglycemia AMERICAN HOME PROD (US) 2001-08-15 CN claimed
US-5817720-A GRAFT POLYMERS ENICHEM S.P.A. (IT) 1998-10-06 US claimed
EP-0792893-A2 Polyolefins modified with an unsaturated polyfunctional monomer containing an imide group and an ester group ENICHEM S.p.A. (IT) 1997-09-03 EP claimed
US-20260083653-A1 COMPONENT SYSTEM AND METHOD FOR PREPARING A TOOTH WHITENING PREPARATION COBEA AG (CH) 2026-03-26 US disclosed
US-12479858-B2 Macrocyclic compounds as sting agonists and methods and uses thereof LUPIN LIMITED (IN) 2025-11-25 US disclosed
EP-4590264-A1 COMPONENT SYSTEM AND METHOD FOR PREPARING A TOOTH WHITENING PREPARATION Cobea AG (CH) 2025-07-30 EP disclosed
CN-119894496-A Component systems and methods for preparing tooth whitening formulations 可碧股份有限公司 2025-04-25 CN disclosed
US-12173026-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2024-12-24 US disclosed
EP-0325289-A1 Bleaching agents comprising imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
EP-0325288-A1 Imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
US-RE32868-E Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1989-02-14 US disclosed
EP-0072286-B1 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1986-10-29 EP disclosed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479858-B2 Macrocyclic compounds as sting agonists and methods and uses thereof STING1, CGAS, MAVS KMT2A 4765/4885MEN1 1550/4885HSD17B10 4510/4885
US-12173026-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT3 KMT2A 94/4885MEN1 1061/4885HSD17B10 1059/4885
US-20260083653-A1 COMPONENT SYSTEM AND METHOD FOR PREPARING A TOOTH WHITENING PREPARATION PRKX, PRKACA, CAPN1 KMT2A 4400/4885MEN1 4878/4885HSD17B10 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.