Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | GPR39 | O43194 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530624 | 0.88 | KDM4E (0.44) | CNR1MAPTUSP1WDR48KDM4E | |
| SCHEMBL13530575 | 0.88 | MAPT (0.40) | TP53MAPTUSP1WDR48FABP4 | |
| SCHEMBL13530517 | 0.86 | CNR1 (0.52) | CNR1CCNE2CCNE1CDK2CNR2 | |
| SCHEMBL13530514 | 0.86 | KDM4E (0.42) | CNR1CCNE2CCNE1CDK2STK17A | |
| SCHEMBL17011538 | 0.83 | EGFR (0.38) | TDP1USP1WDR48KDM4EALDH1A1 | |
| SCHEMBL13530543 | 0.82 | VNN1 (0.45) | CNR1TP53MAPTADORA2ATDP1 | |
| SCHEMBL13530529 | 0.82 | CNR1 (0.42) | CNR1CCNE2CCNE1CDK2GPR39 | |
| SCHEMBL13530553 | 0.81 | CNR1 (0.43) | CNR1STK17ACNR2 | |
| SCHEMBL13530571 | 0.81 | CNR1 (0.41) | CNR1STK17AKDM4EALDH1A1CNR2 | |
| SCHEMBL13530519 | 0.81 | CNR1 (0.51) | CNR1KDM4EALDH1A1HPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9204653-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-9204653-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-9174970-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9174970-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
| US-20090203647-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203647-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | CNR1 4592/4885CCNE2 2880/4885CCNE1 1728/4885 |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | CNR1 4592/4885CCNE2 2880/4885CCNE1 1728/4885 |
| US-20090203647-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | CNR1 4592/4885CCNE2 2880/4885CCNE1 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.